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. 2009 Mar 18;101(6):374–383. doi: 10.1093/jnci/djp001

Figure 4.

Figure 4

Age-adjusted [to the US standard million (21)] incidence in men aged 50–84 years of local–regional-stage and distant-stage prostate cancer as observed (SEER 9) and predicted by each of the models. A) Local–regional-stage prostate cancer. B) Distant-stage prostate cancer. SEER 9 = the nine core catchment areas in the Surveillance, Epidemiology, and End Results program of the National Cancer Institute; MISCAN = microsimulation screening analysis model based on ERSPC Rotterdam, calibrated to SEER 9 incidence; FHCRC = microsimulation model developed at the Fred Hutchinson Cancer Research Center, explicitly linking PSA levels and prostate cancer development; UMich = analytic model developed by A. Tsodikov (University of Michigan); PSA = prostate-specific antigen; ERSPC = European Randomized Study of Screening for Prostate Cancer.