Table 3.
Characteristics of REGARDS Renal Ancillary Study Participants by Anemia Status, Overall and by Race, United States, 2003–2007
Characteristica | Anemia |
Anemic Subjects by Race |
||||||||
No (n = 17,027) |
Yes (n = 2,809) |
P Value (Anemia vs. no Anemia) | White (n = 976) |
Black (n = 1,833) |
P Value (White vs. Black)b | |||||
No. | % | No. | % | No. | % | No. | % | |||
Demographics | ||||||||||
Age in years, mean (SD) | 64.1 (9.7) | 66.6 (10.4) | <0.001 | 69.2 (10.5) | 65.3 (10.1) | <0.001 | ||||
Female gender | 10,489 | 62 | 1,851 | 66 | <0.001 | 558 | 57 | 1,293 | 71 | <0.001 |
Living in the southeast | 9,999 | 59 | 1,771 | 63 | <0.001 | 652 | 67 | 1,119 | 61 | 0.003 |
Socioeconomic variables | ||||||||||
High school education | 15,306 | 90 | 2,290 | 82 | <0.001 | 884 | 91 | 1,406 | 77 | <0.001 |
Annual income | <0.001 | <0.001 | ||||||||
<$25,000 | 2,670 | 18 | 675 | 28 | 147 | 18 | 528 | 34 | ||
$25,000–$75,000 | 6,508 | 44 | 1,152 | 48 | 414 | 50 | 738 | 48 | ||
>$75,000 | 5,701 | 38 | 560 | 23 | 275 | 33 | 285 | 18 | ||
Medical conditions | ||||||||||
Vascular disease | 3,245 | 19 | 833 | 30 | <0.001 | 358 | 37 | 475 | 26 | <0.001 |
Diabetes | 2,852 | 17 | 1,074 | 38 | <0.001 | 322 | 33 | 752 | 41 | <0.001 |
Hypertension | 9,212 | 54 | 2,012 | 72 | <0.001 | 612 | 63 | 1,400 | 77 | <0.001 |
Ever smoker | 8,992 | 53 | 1,355 | 48 | <0.001 | 500 | 51 | 855 | 47 | 0.019 |
Body mass index in kg/m2, mean (SD) | 29.2 (6.2) | 30.5 (7.1) | <0.001 | 28.5 (6.4) | 31.5 (7.3) | <0.001 | ||||
Anemia-associated conditions | ||||||||||
Chronic kidney disease | 1,368 | 8 | 727 | 26 | <0.001 | 334 | 34 | 393 | 22 | <0.001 |
Inflammation | 1,366 | 8 | 482 | 17 | <0.001 | 134 | 14 | 347 | 19 | <0.001 |
Mean corpuscular volume | <0.001 | <0.001 | ||||||||
Low (≤80 fL) | 553 | 3 | 517 | 19 | 109 | 11 | 408 | 22 | ||
Normal (81–99 fL) | 15,993 | 95 | 2,195 | 79 | 815 | 84 | 1,380 | 76 | ||
High (≥100 fL) | 327 | 2 | 74 | 3 | 42 | 4 | 32 | 2 |
Abbreviations: REGARDS, REasons for Geographic And Racial Differences in Stroke; SD, standard deviation.
Definitions are provided in the Materials and Methods section of the text.
P values reflect black-white differences in those with anemia, taking into account the different prevalences of the conditions by race in the entire cohort.