Table 1.

Effects of various doses of ethanol on plasma tryptophan concentration and availability to the brain

	Dose of ethanol (g/kg body weight)
Parameter	0	0.2	0.4	0.6	0.8
[Trp]	38 ± 3	28 ± 3*	22 ± 1*	20 ± 1*	18 ± 1*
[CAA]	405 ± 39	402 ± 44	363 ± 32	344 ± 29	318 ± 24
[Trp]/[CAA]	0.094 ± 0.009	0.069 ± 0.011	0.061 ± 0.006*	0.058 ± 0.006*	0.057±.003*

Values (in μM or ratio) are means ± SEM for n = 10 per group.

^*P = 0.0264 at least (one-way ANOVA with replicated measures).