TABLE 2.
Summary of the single nucleotide substitutions generated by the two RTs.
| HIV-1 | PFV | |
|---|---|---|
| Transversions | ||
| C→A | 21 | 15 |
| T→A | 17 | 6 |
| G→C | 4 | 1 |
| T→G | 1 | 1 |
| A→C | 1 | 4 |
| C→G | 0 | 6 |
| G→T | 0 | 2 |
| 44 | 35 | |
| Transitions | ||
| C→T | 13 | 4 |
| G→A | 80 | 25 |
| A→G | 11 | 5 |
| T→C | 2 | 1 |
| 106 | 35 | |
| Overall Error rate | 6.3 × 10−5 | 5.8 × 10−5 |
The number of transitions and transversions, as well as the type of base substitution, is shown. The error rate for transitions and transversions combined were calculated in a manner similar to that described for Table 1, except the number of single nucleotide substitutions were used.