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. Author manuscript; available in PMC: 2010 Apr 15.
Published in final edited form as: J Immunol. 2009 Apr 15;182(8):4899–4909. doi: 10.4049/jimmunol.0803242

Figure 11. Protection Against Mucosal F. tularensis SchuS4 Challenge is Also Enhanced in Mice Immunized With iFt Plus CTB.

Figure 11

C57BL/6 mice were divided into four groups (8 mice/group) and immunized i.n. with 20μl of PBS, 5μg of CTB in 20 μl PBS, 2 × 107 iFt in 20 μl PBS, or 2 × 107 iFt with 5μg of CTB in 20 μl PBS. Mice subsequently received an immunization boost on days 14 and 28. Mice were then challenged on day 42 i.n. with 23 CFU (approximately 10–20 × LD50) of live F. tularensis SchuS4, and subsequently monitored for survival. The figure is representative of data from three different experiments.