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. Author manuscript; available in PMC: 2010 Apr 15.
Published in final edited form as: J Immunol. 2009 Apr 15;182(8):4899–4909. doi: 10.4049/jimmunol.0803242

Figure 2. Bacterial Burden is Reduced in Mice Immunized With iFt Plus CTB as Compared to Mice Immunized With iFt Alone.

Figure 2

BALB/c mice were immunized as described in Figure 1. Bacterial burden studies were then conducted as described in Materials and Methods. Briefly, lung (A), liver (B), and spleen (C) were harvested at 1, 3, 7, and 14 days post-challenge and bacterial counts were carried out. Each point represents the average of three mice sacrificed per time point + SD. On day 7 iFt plus CTB-immunized mice had significantly lower bacterial burden in tissues than iFt-treated mice (p<0.001). On day 14, all mice immunized with PBS or CTB alone succumbed to the infection, as indicated by a cross (+) on the x-axis. The data is representative of two experiments.