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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Nucl Med Biol. 2009 Aug;36(6):671–680. doi: 10.1016/j.nucmedbio.2009.04.002

Figure 4.

Figure 4

Paired-label internalization of scFv-Fc DM fragment radiolabeled with [125I]IB-Mal-D-GEEEK (squares) and [131I]SGMIB (triangles) in MCF7-HER2 cells. Cells were incubated with the tracer pair at 4°C for 1 h, and after removal of the unbound radioactivity, brought to 37°C and processed at various time periods. Data shown are the percent of initially bound radioactivity that was trapped intracellularly.