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. 2000 Nov 14;97(24):13245–13250. doi: 10.1073/pnas.230442897

Figure 5.

Figure 5

Structure-based dendrogram of inferred relationships between Ig domain-containing receptors. An all-against-all structural distance matrix was determined using FcγRIIb domain (D)2 (PDB entry name 2FCBA), human KIR-D2 (1NKR), β2 μ-D1 (1BMG), Hemolin-D1 (1BIH), TrkB-D1 (1WWB), CD2-D1 (1HNF), CD4-D1 (3CD4), CD8-D1 (1CD8), ICAM-D1 (1IAM), MadCAM-D1 (1BQS), and HTF-D1 (1BOY). The optimal tree topology was estimated by parsimony analysis with global rearrangements. With the exception of FcγRIIb and KIR, domain classifications are indicated along branches according to the SCOP database. A fibronectin type III (HTF) domain serves as an outgroup to root the tree.