Modified Pathologic Diagnosis (MPD) criteria. A&B. MPD positive includes the same features as for CPD. Additionally, focal chronic inflammation in any layer of the artery wall (arrow), including surrounding vasa vasora, are included. C&D. MPD indeterminate includes the same features as for CPD. Additionally, a focal concentric scar around the inner elastic lamina for any number of clock hours (between arrows) with loss of the inner elastic lamina (*) are included. E&F. MPD negative is the same as for CPD negative. The inner elastic lamina (arrows) is intact. (hematoxylin and eosin, A, C, E 25X; B, D, F 100X)