Table 3.
Effects of Sp-cAMPS on performance on the variable-short inter-trial interval version of the 5CSRTT
Vehicle | Sp-cAMPS (2.1 nmol/0.5 μl/side) | |||||||
---|---|---|---|---|---|---|---|---|
| ||||||||
0.5-s | 1.5-s | 3.0-s | 4.5-s | 0.5-s | 1.5-s | 3.0-s | 4.5-s | |
| ||||||||
% Accuracy |
48.4 ± 8.0 | 67.1 ± 3.9* | 67.5 ± 5.8* | 72.9 ± 4.9* | 53.6 ± 6.3 | 73.4 ± 3.1* | 80.0 ± 3.4* | 74.1 ± 3.4* |
% Omissions | 60.0 ± 6.2 | 39.1 ± 6.5* | 20.3 ± 5.3* | 13.6 ± 4.8* | 55.2 ± 4.4 | 38.2 ± 4.6* | 25.2 ± 5.8* | 23.0 ± 6.3* |
Note: There was an ITI duration-dependent effect on both accuracy and omissions whereby accuracy was impaired at the shortest ITI (0.5-s) and omissions were increased at the shortest ITI compared to the longer ITIs, but Sp-cAMPS did not further affect performance at any ITI.
P<0.05, within-subjects comparison.