Table 14.
Genes involved in ATP binding
| Gene symbol | Probe set | Ratio CSE/Con | p-value | Description | GO Biological Process | GO Molecular Function | GO Cellular Component | Pathway |
|---|---|---|---|---|---|---|---|---|
| ATP6V1H | 33741_at | 1.25 | 0.01 | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | ATP synthesis coupled proton transport / proton transport | ATP binding / hydrogen-transporting ATP synthase activity, rotational mechanism / hydrogen-transporting ATPase activity, rotational mechanism / hydrolase activity | proton-transporting two-sector ATPase complex | Oxidative phosphorylation / ATP synthesis / Photosynthesis / Flagellar assembly / Type III secretion system |
| IKBKB | 35960_at | 1.25 | 0.03 | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | protein amino acid phosphorylation | ATP binding / protein serine/threonine kinase activity / transcriptional activator activity / transferase activity | cytoplasm | --- |
| ABCC1 | 1896_s_at | 1.25 | 0.04 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | protein amino acid phosphorylation / response to drug / transport | ATP binding / ATPase activity, coupled to transmembrane movement of substances / nucleotide binding / protein kinase activity / transporter activity | integral to membrane / integral to plasma membrane / membrane fraction | --- |
| PDK2 | 38844_at | 1.25 | 0.04 | pyruvate dehydrogenase kinase, isoenzyme 2 | glucose metabolism / protein amino acid phosphorylation | ATP binding / [pyruvate dehydrogenase (lipoamide)] kinase activity / protein kinase activity / transferase activity | mitochondrion | Krebs-TCA_Cycle |
| ADRBK1 | 38447_at | 1.11 | 0.002 | adrenergic, beta, receptor kinase 1 | protein amino acid phosphorylation / signal transduction | ATP binding / G-protein coupled receptor kinase activity / beta-adrenergic-receptor kinase activity / signal transducer activity / transferase activity | cytoplasm / soluble fraction | --- |
| PRKACA | 438_at | 1.11 | 0.004 | protein kinase, cAMP-dependent, catalytic, alpha | protein amino acid phosphorylation | ATP binding / cAMP-dependent protein kinase activity / protein serine/threonine kinase activity / transferase activity | cAMP-dependent protein kinase complex / nucleus | G_Protein_Signaling / Phosphatidylinositol signaling system |
| 39456_at | 1.11 | 0.02 | Clone IMAGE 23915 | protein amino acid phosphorylation | ATP binding / protein serine/threonine kinase activity / protein-tyrosine kinase activity / transferase activity | --- | --- | |
| PCTK1 | 1225_g_at | 1.11 | 0.02 | PCTAIRE protein kinase 1 | protein amino acid phosphorylation / regulation of cell cycle | ATP binding / protein serine/threonine kinase activity / transferase activity | --- | Phosphatidylinositol signaling system |
| DYRK4 | 101_at | 1.11 | 0.04 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 | protein amino acid phosphorylation | ATP binding / protein serine/threonine kinase activity / protein-tyrosine kinase activity / transferase activity | --- | --- |
| STK16 | 31868_at | 1.11 | 0.04 | serine/threonine kinase 16 | protein amino acid phosphorylation / protein complex assembly | ATP binding / protein serine/threonine kinase activity / protein-tyrosine kinase activity / transferase activity | --- | --- |
| FARS1 | 36504_at | 1.11 | 0.05 | phenylalanine-tRNA synthetase 1 (mitochondrial) | phenylalanyl-tRNA aminoacylation / tRNA processing | ATP binding / phenylalanine-tRNA ligase activity / tRNA binding | mitochondrion / soluble fraction | --- |
| KRTHA3 B | 34568_at | 0.91 | 0.03 | keratin, hair, acidic, 3B | --- | structural molecule activity | intermediate filament | --- |
| ERBB3 | 1742_at | 0.91 | 0.03 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | protein amino acid phosphorylation / transmembrane receptor protein tyrosine kinase signaling pathway | ATP binding / epidermal growth factor receptor activity / receptor activity / transferase activity | integral to plasma membrane | --- |
| MAP3K7 | 36905_at | 0.83 | 0.02 | mitogen-activated protein kinase kinase kinase 7 | protein amino acid phosphorylation / transforming growth factor beta receptor signaling pathway | ATP binding / MAP kinase kinase kinase activity / magnesium ion binding / protein serine/threonine kinase activity / protein-tyrosine kinase activity / transferase activity | --- | --- |
| DDX42 | 38762_at | 0.77 | 0.04 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 | --- | ATP binding / ATP-dependent helicase activity / hydrolase activity / nucleic acid binding | --- | --- |
| FGFR2 | 1363_at | 0.71 | 0.03 | fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) | protein amino acid phosphorylation | ATP binding / fibroblast growth factor receptor activity / protein serine/threonine kinase activity / protein-tyrosine kinase activity / receptor activity / transferase activity | integral to membrane | --- |
| BAT1 | 35292_at | 0.71 | 0.04 | HLA-B associated transcript 1 | --- | ATP binding / ATP-dependent RNA helicase activity / RNA binding | nucleus | --- |
| SMC5L1 | 41379_at | 0.67 | 0.02 | SMC5 structural maintenance of chromosomes 5-like 1 (yeast) | chromosome segregation | ATP binding | nucleus | --- |