Table 4.
Association between (-670 A/G) Apo1/Fas gene polymorphism and location of lesion
| ApoI/Fas |
UC (n = 59) |
CD (n = 105) |
|||||
| G/G | G/A | A/A | G/G | G/A | A/A | ||
| Distal | 4 | 9 | 8 | Ileum | 5 | 10 | 12a |
| Left-sided olitis | 5 | 15 | 6 | Colon | 13b | 8 | 3 |
| Pancolitis | 3 | 8 | 1 | Ileocolon | 16 | 22 | 16 |
a
χ2 test between AA genotype and ileum location of lesion in CD patients (χ2 = 3.89, two degrees of freedom, P corrected = 0.048) odds ratio is 2.48 (0.90 < OR < 6.87, CI = 95%);
b
χ2 test between GG genotype and colon location of lesion in CD patients (χ2 = 6.74, two degrees of freedom, P corrected = 0.009) odds ratio is 3.38 (1.19 < OR < 9.67, CI = 95%).