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The temporal kinetics of Th–Th associative recognition. C57BL/6 mice were immunized with plasmid γ1NV2VTSA3, and the proliferative response of spleen cells was measured at the time of harvest indicated. The concentration (μg/ml) of synthetic peptide VTSA or NVDP in culture is indicated. Values represent the mean stimulation index ± SD of 4 mice per group.
