Table 3.

Association between creatinine-based estimated glomerular filtration rate (eGFR) and mitral annular calcifications (MAC), aortic annular calcifications (AAC) and aortic valve sclerosis (AVS)

eGFR
	>60 mL/min/1.73 m2	45–60 mL/min/1.73 m2	<45 mL/min/1.73 m2	P for trend
	N = 2777	N = 710	N = 214
MAC
Model 1a	Reference	0.97 (0.82–1.15)	1.65 (1.24–2.20)	0.019
Model 2b	Reference	0.94 (0.79–1.11)	1.54 (1.16–2.06)	0.082
AAC
Model 1a	Reference	0.98 (0.82–1.17)	1.36 (1.02–1.82)	0.169
Model 2b	Reference	0.95 (0.80–1.14)	1.30 (0.97–1.74)	0.340
AVS
Model 1a	Reference	1.01 (0.85–1.20)	1.22 (0.91–1.62)	0.299
Model 2c	Reference	0.98 (0.82–1.16)	1.15 (0.86–1.53)	0.599

MAC, AAC and AVS were defined as present or absent, i.e. summing mild, moderate or severe versus none. Data presented as OR (95% confidence intervals).

^aAdjusted for age, gender and race.

^bAdjusted for age, gender, race, prevalent cardiovascular disease and HDL-cholesterol.

^cAdjusted for age, gender, race, prevalent cardiovascular disease, hypertension, HDL-cholesterol and waist-hip-ratio.