Fig. 4.

Multivariable-adjusted log hazards ratios (95% confidence intervals) of the composite outcome of pre-dialysis mortality or end-stage renal disease associated with baseline levels of serum bicarbonate in a fixed-covariate Cox model adjusted for age, race, body mass index, comorbidity index, diabetes mellitus, cardiovascular disease, systolic blood pressure, proteinuria, estimated glomerular filtration rate, serum phosphorus and albumin, white blood cell count, percentage of lymphocytes and use of medications.