Table 3.
Clinicopathology parameters | Case (n) |
PTEN protein expression (n) |
Positive rate (%) | P | |
Negative | Positive | ||||
Tissues | |||||
Paracancerous | 53 | 0 | 53 | 100.0 | < 0.005 |
Gastric cancer | 53 | 18 | 35 | 66.0 | |
Gender | |||||
Male | 41 | 15 | 26 | 63.4 | |
Female | 12 | 3 | 9 | 66.7 | |
Age (yr) | |||||
≤ 60 | 14 | 5 | 9 | 64.3 | |
> 60 | 39 | 13 | 26 | 66.7 | |
Size (cm) | |||||
≤ 3 | 16 | 6 | 10 | 68.8 | |
> 3 | 37 | 12 | 25 | 64.9 | |
Location | |||||
Antrum | 30 | 10 | 20 | 66.7 | |
Gastric body and cardia | 23 | 8 | 15 | 65.2 | |
Infiltrating depth | |||||
T1, T2 | 14 | 1 | 13 | 92.9 | < 0.025 |
T3 | 15 | 6 | 9 | 60.0 | |
T4 | 24 | 11 | 13 | 54.2 | |
Lymph node metastasis | |||||
Without | 21 | 2 | 19 | 90.5 | < 0.01 |
With | 32 | 16 | 16 | 50.0 | |
Distant metastasis | |||||
Without | 45 | 15 | 30 | 66.7 | |
With | 8 | 3 | 5 | 62.5 | |
Embolization | |||||
Without | 8 | 1 | 7 | 87.5 | |
With | 45 | 15 | 30 | 66.7 | |
Differentiation extent | |||||
Moderate and high | 26 | 4 | 22 | 84.6 | < 0.025 |
Low | 27 | 14 | 13 | 48.1 | |
PTNM staging | |||||
I, II | 19 | 1 | 18 | 94.7 | < 0.005 |
III, IV | 34 | 17 | 17 | 50.0 |