Table 1.
Tumor formation ability of sorted pancreatic cancer cells using surface markers (number of tumors formed/number of injections)
Groups | 5×105 | 105 | 5×104 | 104 | 5×103 | 103 | 102 |
Unsorted | 6/6 | 5/6 | 3/6 | 1/6 | 0/6 | 0/0 | 0/0 |
CD44+ | 0/0 | 9/10 | 6/10 | 3/10 | 1/6 | 0/4 | 0/0 |
CD44 | 0/0 | 2/10 | 1/10 | 0/4 | 0/0 | 0/0 | 0/0 |
P | 0.0027 | 0.0286 | 0.3297 | ||||
CD24+ | 0/0 | 7/8 | 4/8 | 3/8 | 0/4 | 0/0 | 0/0 |
CD24 | 0/0 | 2/8 | 1/8 | 0/8 | 0/0 | 0/0 | 0/0 |
P | 0.0203 | 0.1410 | 0.1000 | ||||
CD44+ CD24+ | 0/0 | 8/8 | 7/8 | 6/8 | 4/8 | 2/8 | 0/4 |
CD44 CD24 | 0/0 | 1/8 | 1/8 | 0/8 | 0/8 | 0/8 | 0/0 |
P | 0.0007 | 0.0051 | 0.0035 | 0.0385 | 0.2333 |
Compared with results from marker-negative cells.