Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Sphingosine-1-phosphate (S1P) metabolism. De novo synthesis of sphingolipids produces ceramide and sphingomyelin. Sphingomyelinase, ceramidase, and sphingosine kinase are required to produce S1P. The degradation of S1P is achieved by the enzymes S1P phosphatase and S1P lyase.
