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. 2009 Aug 13;4(8):e6635. doi: 10.1371/journal.pone.0006635

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Smolders et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Within the CD3⁺CD4⁺ lymphogate, Tregs were defined as either being (A) CD25⁺FoxP3⁺ or being (B) CD25⁺CD127⁻. (C) The percentages of Tregs within the CD4⁺ T cell compartment. (D) Absolute number of circulating Tregs. The lines indicate the median values.