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Inhibited upregulation of antioxidant genes at 48 hpf in NRF2 knockdown (NRF2-MO) compared to control morpholino (CO-MO)–injected embryos after a 24-h exposure to DMSO, 1 μg/l BNF, 100 μg/l ANF, or a combination of BNF + ANF. There was a significant interaction between injection and treatment (p ≤ 0.003) in two-way ANOVAs. (*p ≤ 0.004; mean + SEM, n = 3).
