Table 2.

Crystallographic and refinement statistics

RNA:ligand	GR:Xanthine	GR:2FA	GR:OMG	GR:6ClG	GRA:OMG	GRA:6ClG	GR(A21G/U75C): 6ClG	GR:2AP
Data collection
Space group	C2	C2	C2	C2	C2	C2	C2	C2
Cell dimensions
a, b, c (Å)	131.35, 35.10, 42.25	132.46, 35.08, 41.89	133.18, 35.27, 42,12	132.10, 35.12, 41.81	130.94, 35.04, 42.19	132.60, 35.17, 41.79	132.51, 35.12, 41.76	127.42, 35.16, 42.24
β(°)	90.38	90.10	90.45	90.03	89.16	90.38	90.57	91.18
Resolution (Å)	20-1.90 (1.97-1.90)a	20-1.95 (2.02-1.95)	20-1.85 (1.92-1.85)	20-1.56 (1.62-1.56)	20-2.15 (2.23-2.15)	20-1.8 (1.86-1.80)	20-2.1 (2.18-2.10)	20-2.4 (2.49-2.4)
Rmerge	0.064 (0.197)	0.059 (0.315)	0.066 (0.323)	0.080 (0.377)	0.096 (0.357)	0.048 (0.201)	0.085 (0.352)	0.080 (0.284)
I/σI	10.2 (3.2)	10.2 (3.2)	11.1 (2.0)	13.1 (2.1)	11.6 (3.0)	15.8 (3.8)	8.5 (3.5)	8.1 (3.0)
Completeness (%)	95.6 (80.6)	95.6 (80.6)	88.1 (53.1)	99.0 (94.0)	90.9 (91.4)	91.8 (69.5)	98.8 (97.6)	94.2 (86.0)
Redundancy	3.58 (3.21)	3.58 (3.21)	3.22 (2.48)	6.73 (5.49)	6.65 (6.67)	3.56 (3.31)	4.91 (4.94)	1.83 (1.12)
Refinementb
Resolution (Å)	20-1.90	20-1.95	20-1.90	20-1.70	20-2.15	20-1.90	20-2.1	20-2.4
Rwork / Rfree	21.0/24.6	21.8/26.8	22.6/27.6	21.6/23.4	23.8/28.3	22.7/25.1	22.0/25.6	22.9/27.8
Average B-factors (Å2)	26.6	39.8	34.9	28.1	40.1	28.0	40.0	40.1
Luzzati error (Å)c	0.28	0.39	0.36	0.24	0.47	0.29	0.37	0.43
rmsd bond lengths (Å)	0.004	0.013	0.012	0.003	0.005	0.004	0.001	0.003
rmsd bond angles (°)	1.1	1.6	1.70	0.9	1.0	1.0	1.0	0.6
PDBID	3GAO	3GOT	3FO6	3GER	3GES	3FO4	3GOG	3G4M

^aHighest resolution shell is shown in parenthesis.

^bRefinement was against all data within the stated resolution range, with a random 10% omitted for use in calculation of R_free

^cCross-validated Luzzati coordinate error