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Southern Blot analysis of single-copy (A) and double-copy (B) Ank/Aγ-globin provirus in CFU-S colonies. Each lane contains 10 μg of DNA isolated from a single dissected CFU-S digested with HindIII. The sizes of the bands indicated at the right indicate the predicted size of the intact provirus. +C, EcoRI-digested DNA from a transgenic mouse with 1 intact copy of the Ank/Aγ-globin gene.
