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. Author manuscript; available in PMC: 2010 Mar 15.
Published in final edited form as: J Immunol. 2009 Mar 15;182(6):3866–3876. doi: 10.4049/jimmunol.0713949

Fig. 10. BALF and Lung Homogenate Cytokines.

Fig. 10

Wildtype (white bar) and Mmp28−/− mice (black bar) were exposed to aerosolized P. aeruginosa and harvested at 4 and 24 h for whole lung homogenates of the right lung, and BALF from the left lung. The levels of several chemokines and cytokines were assessed from these two compartments using luminex-based assays and ELISAs. KC and MIP-2 are significantly decreased in the BALF and LH of Mmp28−/− mice, 4 h post-infection. There is no difference in MCP-1 or MIP-1α levels. TNF-alpha, IL-6 and GM-CSF are significantly increased in the BALF, but not LH of Mmp28−/− mice, 4 h post-infection. Data are means ± SEM, results represent 10 mice/timepoint. (*p value <0.05)