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. Author manuscript; available in PMC: 2010 Mar 15.
Published in final edited form as: J Immunol. 2009 Mar 15;182(6):3866–3876. doi: 10.4049/jimmunol.0713949

Fig. 9. Macrophage-Deficient Mice have impaired bacterial clearance and increased pulmonary neutrophilia.

Fig. 9

(A-C) Results from control WT (white bar) and Mmp28−/− (grey bar) mice vs. clodronate-treated WT (white striped bar) and Mmp28−/− (grey striped bar) mice. All groups have been treated with intranasal instillation of P. aeruginosa (1 × 107 organisms/lung) and harvested at 4 and 24 h for BALF cell counts, differential and bacterial clearance. (A) BALF neutrophil cell counts at 4 and 24 h post-infection, (B) BALF macrophage cell counts at 4 and 24 h post-infection, (C) Whole lung bacterial counts (CFU) 4 h after infection. *p value < 0.05 when compared to same genotype mice.