Table 5.
Change (coefficient) in birth weight (g) for an IQR increase (μg/m3) in exposure to NO2 and BTEX at the entire pregnancy period and each trimester in 570 newborns from INMA-Sabadell.
| Birth weight [g (95% confidence interval)]
|
|||
|---|---|---|---|
| All women (n = 570) | Women who spent ≥ 15 hr/day at home (n = 276) | Women who spent < 2 hr/day in nonresidential outdoor environments (n = 259) | |
| Crude
| |||
| NO2 | |||
| 9 Months | −6.1 (−43.3 to 31.2) | −21.4 (−75.9 to 33.2) | −14.4 (−68.5 to 39.6) |
| First trimester | −4.5 (−45.2 to 36.2) | −6.1 (−67.4 to 55.2) | −1.2 (−61.4 to 59.1) |
| Second trimester | −18.1 (−57.5 to 21.4) | −45.2 (−103.4 to 12.9) | −46.2 (−103.7 to 11.2) |
| Third trimester | 4.8 (−36.2 to 45.7) | −7.4 (−67.4 to 52.6) | 6.7 (−52.2 to 65.6) |
| BTEX | |||
| 9 Months | −9.6 (−62.8 to 43.6) | −37.2 (−114.5 to 40.1) | −61.9 (−140.0 to 17.6) |
| First trimester | −10.9 (−66.1 to 44.3) | −27.3 (−110.3 to 55.7) | −50.0 (−132.0 to 32.1) |
| Second trimester | −26.4 (−84.5 to 31.7) | −68.0 (−152.8 to 16.8) | −98.5 (−184.0 to −13.0)* |
| Third trimester | 6.5 (−47.7 to 60.8) | −15.8 (−94.7 to 63.0) | −29.7 (−110.7 to 51.2) |
| Adjusted (each trimester separately)a | |||
| NO2 | |||
| 9 Months | 8.8 (−23.8 to 41.5) | 8.6 (−37.9 to 55.2) | −18.6 (−66.3 to 29.1) |
| First trimester | 3.3 (−33.2 to 39.7) | 9.8 (−43.2 to 62.9) | 4.2 (−49.3 to 57.6) |
| Second trimester | 3.7 (−31.1 to 38.4) | −1.5 (−50.9 to 47.9) | −42.3 (−92.1 to 7.4) |
| Third trimester | 16.8 (−18.8 to 52.4) | 15.8 (−35.1 to 66.6) | −9.0 (−60.5 to 42.6) |
| BTEX | |||
| 9 Months | −7.6 (−54.9 to 39.8) | −13.0 (−79.3 to 53.3) | −76.6 (−146.3 to −7.0)* |
| First trimester | −12.0 (−62.0 to 38.0) | −16.3 (−87.8 to 55.2) | −52.5 (−125.8 to 20.8) |
| Second trimester | −13.3 (−65.1 to 38.4) | −22.5 (−95.1 to 50.0) | −101.9 (−176.2 to −27.6)* |
| Third trimester | 2.5 (−45.3 to 50.4) | −1.4 (−68.8 to 66.0) | −59.7 (−130.9 to 11.5) |
| Adjusted (all trimesters together)b | |||
| NO2 | |||
| First trimester | −7.6 (−56.8 to 41.5) | 12.7 (−63.0 to 88.4) | 54.8 (−18.5 to 128.0) |
| Second trimester | −5.8 (−52.7 to 41.0) | −22.8 (−90.7 to 45.0) | −74.7 (−140.4 to −9.0)* |
| Third trimester | 24.6 (−22.1 to 71.3) | 22.1 (−46.1 to 90.2) | 0.9 (−64.4 to 66.3) |
| BTEX | |||
| First trimester | −19.2 (−101.0 to 62.6) | −13.4 (−139.9 to 113.0) | 60.8 (−61.8 to 183.5) |
| Second trimester | −21.7 (−104.6 to 61.3) | −42.3 (−161.4 to 77.0) | −137.3 (−252.6 to −22.0)* |
| Third trimester | 30.0 (−44.8 to 104.9) | 35.8 (−74.8 to 146.4) | −16.7 (−123.3 to 89.8) |
a
Adjusted for child’s sex, gestational age, season of conception, parity, maternal educational level, maternal smoking during pregnancy, maternal height and prepregnancy weight, and paternal height.
b
Adjusted for above variables and exposures to the same pollutant during the other two trimesters.
*
p < 0.05.