Examples of RR series of 4,096 successive beats, illustrating different aspects of HR variability. Note the asymmetry of the distribution, the low entropy and long-range autocorrelation in patient B, as well as the low entropy in patient C. Patient A (32 weeks postmenstrual age) weighed 1,165 g and had no sepsis. Patient B (30 weeks postmenstrual age) weighed 850 g and had an isolated inflammatory response. Patient C (31 weeks postmenstrual age) weighed 1,345 g and had sepsis. SA = Sample asymmetry; α2 = long-range fractal correlations.