Table 3. Adjusted hazard ratios (95% confidence intervals) for all-cause mortality associated with sleep-disordered breathing,stratified by sex and age in the Sleep Heart Health Study.

Apnea–Hypopnea Index (Events/h)	N	Person–Years	Deaths	Mortality Ratea	Model 1b	Model 2c	Model 3d
Men ≤70 y
<5.0	985	8,220	91	11.1	1.00	1.00	1.00
5.0–14.9	694	5,697	82	14.4	1.10 (0.81–1.48)	1.16 (0.85–1.58)	1.24 (0.90–1.71)
15.0–29.9	322	2,623	47	17.9	1.37 (0.96–1.95)	1.44 (1.00–2.08)	1.45 (0.98–2.14)
≥30.0	168	1,355	28	20.7	1.67 (1.09–2.55)	1.88 (1.19–2.95)	2.09 (1.31–3.33)
Men >70 y
<5.0	277	2,055	125	60.8	1.00	1.00	1.00
5.0–14.9	282	2,176	111	51.0	0.86 (0.67–1.11)	0.89 (0.69–1.16)	0.92 (0.70–1.20)
15.0–29.9	140	1,029	67	65.1	1.18 (0.87–1.58)	1.25 (0.92–1.70)	1.23 (0.90–1.68)
≥30.0	74	517	36	69.6	1.16 (0.80–1.69)	1.25 (0.85–1.83)	1.27 (0.86–1.86)
Women ≤70 y
<5.0	1641	13,902	90	6.5	1.00	1.00	1.00
5.0–14.9	527	4,448	40	9.0	1.00 (0.68–1.45)	0.99 (0.66–1.47)	0.97 (0.64–1.48)
15.0–29.9	161	1,350	14	10.4	1.11 (0.63–1.96)	1.12 (0.62–2.02)	1.15 (0.63–2.11)
≥30.0	63	537	8	14.9	1.73 (0.84–3.58)	1.75 (0.82–3.74)	1.76 (0.77–3.95)
Women >70 y
<5.0	526	4,149	171	41.2	1.00	1.00	1.00
5.0–14.9	294	2,382	86	36.1	0.77 (0.60–1.00)	0.78 (0.60–1.02)	0.77 (0.58–1.00)
15.0–29.9	104	821	37	45.1	0.98 (0.68–1.40)	0.99 (0.69–1.42)	0.89 (0.61–1.31)
≥30.0	36	261	14	53.6	1.09 (0.62–1.89)	1.10 (0.63–1.92)	1.14 (0.65–2.01)

^aCrude mortality rate per 1,000 person years.

^bModel 1: Adjusted for age (continuous) and race.

^cModel 2: Adjusted for covariates of model 1 and body mass index (continuous).

^dModel 3: Adjusted for covariates of model 2, smoking status (never, former, current), systolic and diastolic blood pressure, prevalent hypertension, diabetes, and cardiovascular disease.