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. 2009 Jul 1;29(26):8408–8418. doi: 10.1523/JNEUROSCI.0714-09.2009

Figure 4.

Figure 4.

The fan mutant displays reduced behavioral sensitivity to ethanol. A, The fan mutant shows normal basal locomotor activity. B, The fan mutant is less sensitive to ethanol-evoked hyperlocomotor activity (right). *p < 0.05, **p < 0.01, ***p < 0.001, n = 28 and 35 for fan/fan and +/+, respectively. C, Locomotor activity of WT sibling and the fan mutant after treatment with 3% ethanol in the medium. Ethanol-induced hypo-locomotion is not significantly different between WT sibling and the fan mutant (n = 11 for each genotype). D, Locomotor activity of WT sibling and the fan mutant recovering from 18 min treatment with 3% ethanol in the medium. The fan mutant recovers significantly faster than WT sibling (*p < 0.05, n = 37 and 36 for fan/fan and +/+, respectively).