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Analytical RP-HPLC of crude sample mixture containing recombinant protein TM 1–99. Conditions: linear AB gradient (1% B/min) at a flow-rate of 0.3 ml/min, where Eluent A is 0.05% aq. TFA and Eluent B is 0.05% TFA in acetonitrile; temperature, 25 °C. P denotes desired product.