Table III.

Adjusted ORs with 95% CIs^a for the effect of genotypes on breast cancers: 584 AA women

Locus	Genotype	Total	ER+	ER−	PR+	PR−	HER2+	HER2−
FGFR2 IVS2 + 7033 (rs1219648)	AA	(1)	(1)	(1)	(1)	(1)	(1)	(1)
	AG	1.04 (0.68–1.58)	0.93 (0.55–1.58)	1.48 (0.73–3.00)	1.18 (0.68–2.06)	0.99 (0.52–1.86)	1.43 (0.69–2.98)	1.02 (0.59–1.75)
	GG	0.64 (0.37–1.13)	0.81 (0.41–1.59)	0.86 (0.56–1.33)	0.65 (0.30–1.42)	0.88 (0.40–1.92)	0.82 (0.31–2.20)	0.84 (0.42–1.66)
	Per G allele	0.84 (0.64–1.09)	0.90 (0.65–1.26)	1.18 (0.68–2.06)	0.87 (0.61–1.23)	0.94 (0.64–1.38)	0.96 (0.62–1.49)	0.93 (0.66–1.29)
FGFR2 IVS2 + 906 (rs2981582)	CC	(1)	(1)	(1)	(1)	(1)	(1)	(1)
	CT	0.79 (0.48–1.32)	0.88 (0.47–1.64)	1.06 (0.42–2.66)	0.88 (0.46–1.68)	1.12 (0.49–2.58)	0.64 (0.28–1.43)	1.38 (0.69–2.76)
	TT	0.64 (0.35–1.16)	0.81 (0.40–1.66)	0.55 (0.17–1.79)	0.67 (0.31–1.45)	1.01 (0.39–2.59)	0.60 (0.28–1.43)	1.11 (0.50–2.48)
	Per T allele	0.80 (0.59–1.08)	0.90 (0.63–1.29)	0.77 (0.44–1.32)	0.82 (0.56–1.20)	1.00 (0.63–1.59)	0.76 (0.47–1.23)	1.05 (0.71–1.53)
MAP3K1 rs889312	AA	(1)	(1)	(1)	(1)	(1)	(1)	(1)
	AC	1.24 (0.79–1.94)	1.22 (0.70–2.15)	1.12 (0.52–2.39)	1.02 (0.56–1.87)	1.44 (0.73–2.84)	0.87 (0.41–1.85)	1.51 (0.84–2.71)
	CC	1.86 (0.96–3.60)	2.84 (1.32–6.09)	1.28 (0.38–4.25)	2.85 (1.29–6.28)	1.52 (0.54–4.29)	2.12 (0.8–5.48)	2.40 (1.03–5.57)
	Per C allele	1.33 (0.98–1.81)	1.57 (1.08–2.29)	1.13 (0.66–1.93)	1.52 (1.02–2.26)	1.29 (0.81–2.05)	1.31 (0.80–2.13)	1.54 (1.03–2.29)

^aEstimated from conditional logistic regression adjusted for age at menopause, number of full-term pregnancies and matched on age.