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Telomeric substrates and cyclobutane pyrimidine dimer photoproducts. (A) Telomeric sequences used in the present work. The superscript n in Un (n = 1, 2, and 3, respectively) refers to the loop in which the second T was replaced by U. (B) Adjacent and nonadjacent photoproducts and their nuclease P1 (NP1) digestion products and HF/pyridine hydrolysis products. R = CH3 for thymine, and R = H for uracil. Trans,syn and cis,anti pyrimidine dimers exist as enantiomeric pairs.
