Table 1.

Stereochemistry, base composition, and loop assignment of the NP1 digestion products of UV-irradiated Tel22 shown in Fig. 4B

HPLC peak	Stereochemistry	Base composition
2	—	T=AG*
3	c,s†	T=TA
5	c,a	T(T)=T(A)
		T(A)=T(A)
7	c,a‡	T1(A)=T3(A)
8	t,a‡	T1(A)=T3(A)
9	c,a§	T1(A)=T3(A)
10	c,a and t,a¶	T1(T)=T3(A)
		T1(A)=T3(A)
11	t,a‖	T1(T)=T3(A)

The superscripted number a or b in the NP1 digestion product T^a(X)=T^b(Y) refers to the loop from which the T arose based on the results of uracil substitution.

*Product-ion spectrum shown in Fig. S3B.

^†Product-ion spectrum and hydrolysis products shown in Fig. S2.

^‡Product-ion spectrum and hydrolysis products shown in Fig. 3 C and D.

^§Product-ion spectrum and hydrolysis products shown in Fig. S5.

^¶Could not be assigned to a specific product

^‖Product-ion spectrum and hydrolysis products shown in Fig. S4.