Fig. 1.

Mutationally activated Met induces diverse mammary tumors. (A) Kaplan–Meier analysis demonstrated a slight difference in age of death between multiparous and nulliparous females (P = 0.04). (B) A high incidence of mammary tumor development was observed in both multiparous and nulliparous females. (C) Mammary adenosquamous carcinoma with solid and tubular patterns (animal 28). (D) Mammary squamous cell carcinoma (animal 6) that had significant karyomegaly. (E) Mammary myoepithelioma (animal 2). (F) Hemangiosarcoma (animal 22). (G) Mammary adenocarcinoma with squamous metaplasia and (H) an adenocarcinoma with solid patterns both observed in different mammary glands of animal 13 (solid patterns not shown in image).