Figure 2.

Expression of RGS4 in the soma. (A) Particles label the nucleoplasm and appear subjacent to the nuclear envelope facing nucleopores; arrowheads in bottom inset point to a pore complex with the characteristic cytoplasmic fibril ring (see also Supplementary Fig. 2). Low immunoreactivity in the cytoplasm marks smooth endomembranes and cisterns of the rough endoplasmic reticulum (rer; arrowheads in top inset). (B) RGS4 was not associated with the plasma membrane directly but was found subjacent to portions of the plasmalemma (frame) endowed with SSCs (arrows); the transition of rer to smooth endoplasmic reticulum (ser) is shown between arrowheads. lys, lysosome; mit, mitochondrion. Scale bars: (A) 500 nm; (B) 200 nm.