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. Author manuscript; available in PMC: 2009 Aug 6.
Published in final edited form as: Immunity. 2009 Jan 16;30(1):155–167. doi: 10.1016/j.immuni.2008.12.009

Figure 6. H3K4me3 and H3K27me3 modifications of key transcription factor genes.

Figure 6

(A) H3K4me3 (blue) and H3K27me3 (red) modifications on Tbx21 (Chr11, 96894000-96939000) and Gata3 (Chr2, 9770000-9830000) loci.

(B,C) Freshly isolated nTreg cells were repolarized under neutral condition (ThN) and Th1 conditions for 72 hours. Proportions of Foxp3- and IFN-γ-producing cells (B) and T-bet (C) were determined by intracellular staining and flow cytometry. The data are representative of two independent experiments.

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