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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Bone. 2009 Apr 8;45(1):52–60. doi: 10.1016/j.bone.2009.03.675

Figure 4.

Figure 4

Geranylgeranyl group donor geranylgeraniol (GGOH) (40 µM) fails to antagonize effects of GGTI-2166 (10 µM) or Y-27632 (10 µM) on actin stress fibers. Treatments were for 6 hr in BSA medium. A: Confocal micrographs of cells showing actin stress fibers and focal adhesions. Bars represent 25 µm. B, C: Quantification of parameters. Values are means +/−SEM of responses measured in 2 independent experiments in which 40 cells were imaged and quantified per group. There are no statistically significant differences in edge actin bundle (4C), cellular area, or circularity (data not shown)