Table 3.
P-Values | P-Values | ||||||||
GENE | Ratio | MAS5 | RMA | GCRMA | GENE | Ratio | MAS5 | RMA | GCRMA |
Neuromuscular Junction | Muscle Contraction and Structure | ||||||||
KCNN3 | 12.98 | 0.013 | 0.011 | 0.018 | MYH1 | 8.57 | 0.001 | 0.001 | 0.000 |
COL4A3 | 2.89 | 0.043 | 0.014 | 0.019 | MYH4 | 4.33 | 0.001 | 0.002 | 0.015 |
LAMB2 | 1.74 | 0.042 | 0.018 | 0.015 | NEB | 2.54 | 0.015 | 0.008 | 0.013 |
Excitation Contraction Coupling | MYBPC2 | 2.16 | 0.027 | 0.004 | 0.004 | ||||
PVALB | 62.60 | 0.001 | 0.004 | 0.001 | DMD | 2.11 | 0.023 | 0.020 | 0.027 |
ATP2B2 | 2.60 | 0.033 | 0.023 | 0.021 | LDB3 | 1.93 | 0.030 | 0.015 | 0.015 |
TRDN | 2.38 | 0.028 | 0.019 | 0.017 | Metabolism/Mitochondria Related | ||||
ATP2C1 | 2.30 | 0.046 | 0.047 | 0.041 | WARS | 0.64 | 0.044 | 0.040 | 0.019 |
PDE4DIP | 2.10 | 0.005 | 0.003 | 0.004 | CAV1 | 0.64 | 0.037 | 0.013 | 0.017 |
CALM1 | 1.70 | 0.005 | 0.004 | 0.008 | CERK | 0.63 | 0.033 | 0.006 | 0.014 |
CACNB1 | 1.51 | 0.045 | 0.014 | 0.017 | A2M | 0.62 | 0.015 | 0.016 | 0.010 |
FKBP1A | 0.56 | 0.039 | 0.016 | 0.011 | MDH1 | 0.60 | 0.050 | 0.017 | 0.011 |
Myogenesis/Fiber type pathways | PECI | 0.58 | 0.029 | 0.024 | 0.012 | ||||
GDF8 | 3.65 | 0.025 | 0.032 | 0.007 | MRPL35 | 0.57 | 0.040 | 0.043 | 0.037 |
IGF1 | 2.63 | 0.013 | 0.010 | 0.008 | MRPS18B | 0.56 | 0.009 | 0.002 | 0.001 |
IGFBP5 | 2.48 | 0.002 | 0.000 | 0.000 | SLC25A20 | 0.55 | 0.044 | 0.049 | 0.022 |
PLCB1 | 2.34 | 0.028 | 0.014 | 0.007 | CPT2 | 0.54 | 0.044 | 0.022 | 0.013 |
RASA4 | 2.26 | 0.037 | 0.027 | 0.029 | MRPS12 | 0.53 | 0.044 | 0.008 | 0.010 |
PPP3CA | 1.95 | 0.012 | 0.003 | 0.005 | UCP2 | 0.51 | 0.030 | 0.023 | 0.015 |
PBX1 | 1.86 | 0.028 | 0.010 | 0.007 | MLYCD | 0.48 | 0.017 | 0.004 | 0.001 |
CALM1 | 1.70 | 0.005 | 0.004 | 0.008 | PPIF | 0.48 | 0.014 | 0.011 | 0.010 |
MBNL1 | 1.55 | 0.033 | 0.015 | 0.024 | ADM | 0.47 | 0.019 | 0.012 | 0.018 |
MEF2A | 1.53 | 0.028 | 0.006 | 0.007 | UCP3 | 0.47 | 0.014 | 0.010 | 0.007 |
NEO1 | 1.44 | 0.015 | 0.005 | 0.001 | ALDH6A1 | 0.46 | 0.023 | 0.013 | 0.007 |
HMGB1 | 1.34 | 0.015 | 0.013 | 0.015 | ACSL1 | 0.43 | 0.014 | 0.008 | 0.004 |
Extracellular Matrix | GOT1 | 0.42 | 0.039 | 0.027 | 0.021 | ||||
MFAP5 | 3.64 | 0.012 | 0.004 | 0.014 | TST | 0.41 | 0.015 | 0.002 | 0.001 |
COL4A3 | 2.89 | 0.043 | 0.014 | 0.019 | MT1G | 0.37 | 0.015 | 0.009 | 0.011 |
COL21A1 | 2.86 | 0.021 | 0.022 | 0.015 | LPL | 0.35 | 0.013 | 0.010 | 0.007 |
KAL1 | 2.57 | 0.002 | 0.003 | 0.003 | RETSAT | 0.35 | 0.002 | 0.006 | 0.005 |
MATN2 | 2.24 | 0.013 | 0.011 | 0.007 | MT1M | 0.34 | 0.015 | 0.006 | 0.004 |
CILP | 2.09 | 0.035 | 0.043 | 0.034 | MT1X | 0.32 | 0.014 | 0.012 | 0.010 |
SMC3 | 1.88 | 0.021 | 0.026 | 0.019 | GLUL | 0.31 | 0.018 | 0.017 | 0.013 |
ECM2 | 1.86 | 0.037 | 0.035 | 0.021 | MT2A | 0.29 | 0.015 | 0.013 | 0.011 |
LAMB2 | 1.74 | 0.042 | 0.018 | 0.015 | MT1H | 0.29 | 0.015 | 0.015 | 0.012 |
COL4A1 | 0.51 | 0.048 | 0.032 | 0.015 | MT1F | 0.27 | 0.019 | 0.012 | 0.009 |
BSG | 0.48 | 0.033 | 0.026 | 0.030 | MT1E | 0.26 | 0.012 | 0.006 | 0.005 |
COL4A2 | 0.43 | 0.012 | 0.010 | 0.006 | LIPE | 0.22 | 0.028 | 0.001 | 0.002 |
Table of genes within function groups related to skeletal muscle. Groups defined by ratio is the expression ratio of CP:CTRL. P-values are listed for the three separate preprocessing algorithms used (MAS5, RMA, GCRMA).