Figure 1.

Pedigree of the Chinese glaucoma family. The variations of MYOC and CYP1B1 genes were summarized in this figure of the Chinese family segregating juvenile glaucoma with goniodysgenesis. The MYOC heterozygous mutation, C>T (P370L) in exon 3 was identified in all six patients but not in asymptomatic family members. Two CYP1B1 SNPs, C>G (R48G) in exon 2 and C>T in intron 1, were identified in all six patients and but not in asymptomatic family members except the proband’s paternal grandmother. Abbreviations: MY, MYOC; CY, CYP1B1. Arrow indicates the proband. (III:1).