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Comparative analyses of post-transcriptional regulations in normal and tumoral hepatic cells. HuH7 cells, HepG2 cells, and hepatocytes (as indicated) were transduced once with lentiviral particles expressing the indicated transgene. After 1 week, eGFP protein and mRNA amounts as well as transgene copy number were determined as described in Fig. 3. A, global post-transcriptional regulation. B, mRNA stability. C, translation efficiency. ANOVA, analysis of variance.
