Table 3.

Variables associated with the occurrence of cardiovascular damage in LUMINA (patients by multivariable logistic regression analyses)^a

	Full model			Reduced model
Variables	OR	95% CI	P-value	OR	95% CI	P-value
Age, years	1.07	1.04, 1.11	<0.0001	1.06	1.03, 1.09	<0.0001
Gender (male)	3.23	1.07, 9.09	0.0349	3.57	1.35, 9.09	0.0098
Ethnicity	0.97	0.62, 1.51	0.8912
Education, years	0.85	0.74, 0.97	0.0178	0.84	0.74, 0.94	0.0035
Smoking	2.78	0.98, 7.88	0.0522
Serositis	1.37	0.52, 3.62	0.5199
Interstitial lung disease	0.28	0.04, 1.80	0.1778
Pneumonitis	1.32	0.42, 4.09	6.349
Pulmonary hypertension	2.69	0.37, 19.50	0.3274
Pulmonary haemorrhage	5.48	0.82, 36.65	0.0791	5.02	0.96, 26.15	0.0555
Hypertension	2.08	0.68, 6.49	0.2067
Renal disorderb	1.27	0.46, 3.53	0.6509
SLAM-R at diagnosis	1.01	0.94, 1.09	0.7543
SDI at baseline	1.23	1.03, 1.48	0.0264	1.28	1.09, 1.50	0.003
CRP tertiles
Low	Reference group
Medium	0.36	0.09, 1.36	0.1302
High	1.89	0.69, 5.16	0.2172	2.63	1.17, 5.91	0.0197

^aAdjusted for cardiovascular manifestations, as noted in the text. ^bHistopathological data included.