Table V.
ORs and frequencies by case–control status for 14 PPARA haplotypes relative to all other haplotypes among postmenopausal women in LIBCSP
| Haplotype numbera | rs135542 | rs1800206 | rs4253623 | rs4253699 | rs4253755 | rs4253760 | Control n (%) | Case n (%) | OR (95% CI)b |
| 1 | A | C | A | C | A | G | 55 (5.5) | 53 (5.3) | 1.01 (0.49, 2.09) |
| 2 | A | C | A | C | A | T | 18 (1.9) | 32 (3.2) | 2.03 (0.71, 5.82) |
| 3 | A | C | A | C | G | G | 18 (1.8) | 14 (1.4) | 0.97 (0.23, 4.18) |
| 4 | A | C | A | C | G | T | 55 (5.5) | 53 (5.2) | 0.89 (0.40, 1.99) |
| 5 | A | C | A | T | A | G | 25 (2.5) | 32 (3.2) | 1.64 (0.61, 4.46) |
| 6 | A | C | A | T | G | G | 19 (1.9) | 36 (3.6) | 2.83 (0.93, 8.65) |
| 7 | A | C | A | T | G | T | 414 (41.7) | 396 (39.2) | 0.92 (0.70, 1.20) |
| 8 | A | C | G | C | G | T | 13 (1.5) | 10 (1.0) | 0.77 (0.12, 4.91) |
| 9 | A | C | G | T | G | T | 104 (10.5) | 103 (10.2) | 0.97 (0.59, 1.59) |
| 10 | A | G | A | C | G | G | 11 (1.1) | 30 (3.0) | 5.02 (1.45, 17.39) |
| 11 | A | G | A | T | G | G | 13 (1.3) | 8 (0.8) | 0.47 (0.08, 2.83) |
| 12 | G | C | A | C | G | T | 15 (1.5) | 8 (0.8) | 0.42 (0.05, 3.55) |
| 13 | G | C | A | T | G | G | 11 (1.1) | 11 (1.1) | 1.07 (0.13, 8.67) |
| 14 | G | C | A | T | G | T | 173 (17.4) | 182 (18.0) | 1.19 (0.79, 1.80) |
a
Haplotypes with frequency ≥0.01, minor alleles in bold.
b
Adjusted for age, measured in 5-year age intervals.