Figure 1.

BDNF 3′-UTR contains numerous predicted target sites for miRNAs expressed in human cerebral cortex. Map of BDNF 3′-UTR (human) showing potential miRNA target sites conserved across mammalian species (see also Supplementary Material, Table S3); target sites for miRNAs expressed in moderate to high levels in human cerebral cortex (Supplementary Material, Fig. S1) are shown in black whereas the remaining predicted sites are shown in gray. Notice that miRNAs expressed in moderate to high levels are located in the vicinity of the two proximal poly-A sites in the BDNF 3′-UTR.