Table 2.
Association between A49T genotype and risk of prostate cancer by racial/ethnic group
| Race/ethnicitya | Genotype | OR (95% CI) |
||
|---|---|---|---|---|
| All cases | Localized cases | Advanced cases | ||
| African-Americanb | AA | 1.0 | 1.0 | 1.0 |
| AT/TT | 1.15 (0.53–2.51) | 1.01 (0.41–2.49) | 1.27 (0.40–3.99) | |
| Latinob | AA | 1.0 | 1.0 | 1.0 |
| AT/TT | 1.42 (0.69–2.90) | 1.76 (0.82–3.79) | 0.90 (0.29–2.79) | |
| Whiteb | AA | 1.0 | 1.0 | 1.0 |
| AT/TT | 1.11 (0.63–1.96) | 1.16 (0.62–2.20) | 1.06 (0.47–2.40) | |
| All groupsc | AA | 1.0 | 1.0 | 1.0 |
| AT/TT | 1.16 (0.79–1.69) | 1.23 (0.81–1.88) | 1.01 (0.57–1.79) | |
aJapanese were excluded from the analysis because there were no carriers of the T allele among cases or controls; native Hawaiians were included in the all groups analysis only because there were only T carriers among the controls.
bOR adjusted for age.
cAdjusted for age (<60/60+) and ethnicity.