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Altered expression of p27Kip1 and Sox2 in Eya1bor/bor cochleae. (A–F) Immunostaining of E14.0 (A–I) and E18.5 (G–L) cochlear sections with an anti-p27KIP1 (A–C, J–L), anti-BrdU (G–I) or anti-Sox2 (D–F, M–P). Brackets indicate the prosensory domain (ps) marked by p27KIP1 and Sox2 expression and lack of BrdU-positive cells. The total length of the cochlea duct (between two small arrows) is thinner in the Eya1 mutants. Scale bars: 50 µm.
