Table 2.
Marker expression profile of transplanted GFP-NRP cells
| Marker | SVZa | RMS | OB | AONvp | AONd | Frontal cortex | Occipital cortex | Cerebellum |
|---|---|---|---|---|---|---|---|---|
| β-tubulin III | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ |
| MAP-2 | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ |
| NF-160 (3 DPT only) | − | − | + | + | + | − | − | − |
| NF-200 (7 DPT only) | − | − | ++ | ++ | ++ | ++ | ++ | ++ |
| GFAP | − | − | − | − | − | − | − | − |
| ChAT | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ |
| Glutamate | − | − | ++ | ++ | ++ | − | − | − |
| GABA | − | − | ++ | + | + | − | − | − |
| Synaptophysin | + | ++ | ++++ | ++++ | ++++ | ++++ | ++++ | ++++ |
In all the areas examined, the average percentage of double-labeled cells is represented by using the following symbols: −, no cells expressing the phenotype; +, up to 25% of cells expressing the phenotype; ++, 25–50% of cells expressing the phenotype; +++, 50–75% of cells expressing the phenotype; ++++, >75% of cells expressing the phenotype. (DPT, days after transplantation).