Table 2.

Nox inhibitor, apocynin, decreases MK polyploidy

Ploidy	Control	200 μM apocynin	P
2n	12.94 ± 2.84	14.39 ± 1.31	.468
4n	8.14 ± 1.13	8.56 ± 0.51	.591
8n	6.39 ± 0.15	13.95 ± 1.22	< .001
16n	18.80 ± 1.19	29.83 ± 1.02	< .001
32n	20.13 ± 1.67	12.72 ± 0.76	.002
64n	17.45 ± 2.61	1.24 ± 0.29	< .001

Summary of MK ploidy status in apocynin-treated BM cultures expressed as a percentage ± SD of total MKs collected (summary of 3 independent experiments). Subgroups were compared with the t test.