lsy-9/nhr-67 broadly affects neuronal fate. (A)
Lineage diagram of the ABalppp neuroblast. Neurons whose fate was affected in
lsy-9/nhr-67 mutants are indicated in red, those unaffected are in
blue, and those untested are in black. See Materials and methods for fate
markers used. (B) Representative image of a fate marker lost in
lsy-9/nhr-67 mutants. The transgene used to visualize AUA is
flp-8prom::gfp (=ynIs2022). ynIs2022 is
normally expressed in three cell types: URX, AUA and RMG. nhr-67
mutants specifically affect flp-8 expression in AUA (L/R; red
arrows). For quantification, see Table S1 in the supplementary material.
(C) Summary of all neuronal fates tested in lsy-9/nhr-67
mutant background. 1The dopamine neuron marker was expressed
ectopically in unidentified cells. For markers and alleles used and penetrance
of defects, see Table S1 in the supplementary material.