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. 2009 Jul 29;136(17):2945–2954. doi: 10.1242/dev.035352

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Fig. 4. — A Ptf1a-dependent domain of Neurog2 expression is shown in vivo. (A-C) Immunofluorescence for Neurog2 (green) on transverse sections of E10.5 neural tube from wild-type (A), Ptf1a^Cre/Cre (B), or Ptf1a^W298A/W298A (C) embryos (only the left half is shown). The area in the dashed box is the dI4/5 regions delineated using the neuronal-subtype-specific markers Brn3a (dI1-3, dI5; red) and Pax2 (dI4, dI6-V2; blue). In the Ptf1a mutants, dI4 neurons are mis-specified to dI5 (dI5^*) (Glasgow et al., 2005). Neurog2 expression is attenuated in the Ptf1a mutants in the dI4 domain (dashed boxes). (A′-C′) Higher magnification of the regions boxed in A-C. (Bottom) The number of Neurog2 cells in the dP2/dI2 or the dP4-5/dI4-5 regions in the wild type and each mutant are shown. ^*P<0.001.