Table 2.

Comparisons of depot initiators and non-depot initiators on prior treatment patterns and clinical characteristics immediately preceding depot initiation

Variable	Depot Initiators (n = 39)	Non-Depot Initiators (n = 275)	Comparison P-Value
Prior treatment pattern, * n (%)
Use of oral typical antipsychotics	26 (66.7%)	69 (25.1%)	<.001
Use of oral atypical antipsychotics	19 (48.7%)	164 (59.6%)	.226
Use of antidepressants	11 (28.2%)	128 (46.5%)	.038
Switch/augment oral antipsychotics	17 (43.6%)	37 (13.5%)	<.001
Prior acute psychiatric services, n (%)
Hospitalized in 6 months prior to depot initiation	25 (64.1%)	41 (14.9%)	<.001
Multiple (≥ 2) hospitalizations between enrollment and depot initiation	14 (35.9%)	39 (14.2%)	.001
Hospitalized at or 30 days prior to depot initiation	22 (56.4%)	18 (6.5%)	<.001
Time to first hospitalization post-enrollment, mean (SD)	168.9 (140.8)	373.7 (332.5)	<.001
Emergency psychiatric services**	3 (7.7%)	25 (9.1%)	.999
Prior clinical variables, n (%)
Recent alcohol use**	12 (30.8%)	59 (21.5%)	.220
Recent illicit drug use**	8 (20.5%)	24 (8.7%)	.041
Recent alcohol or illicit drug use**	14 (35.9%)	66 (24.0%)	.119
Violent behavior**	3 (7.7%)	24 (8,7%)	.999
Victim of crime**	6 (16.2%)	36 (13.1%)	.608
Arrested/jailed ***	9 (23.1%)	18 (6.5%)	.002
Suicidal thought or threat**	4 (10.3%)	43 (15.6%)	.478
Suicide attempt**	0 (0)	10 (3.6%)	.619

*During the 3 months prior to depot initiation (for initiators) or prior to the mean time to depot initiation (for non-depot initiators)

**During the 4 weeks prior to the assessment closest to the date of depot initiation (for initiators) or prior to the mean time to depot initiation (for non-depot initiators)

***During the 6 months prior to the assessment closest to the date of depot initiation (for initiators) or prior to the mean time to depot initiation (for non-depot initiators)