Figure 2. Glutathione and glutathione disulfide levels and glutathione peroxidase and reductase activities in rat plantaris.
(A) Plantaris muscles from rats chronically fed alcohol (EtOH) for 35 weeks had reduced levels of glutathione (GSH), an effect that was prevented following 12 weeks of procysteine (PRO) supplementation. (B) Glutathione disulfide (GSSG) levels remained unchanged. Specific enzyme activities of both (C) glutathione peroxidase and (D) glutathione reductase were reduced in plantaris muscles from alcohol-fed rats. These effects were not ameliorated by procysteine supplementation. Values are expressed as means + SEM (n=6-7 rats/group). Significance was accepted at p ≤ 0.05. *, compared to control group. #, compared to EtOH group.